Canine Juvenile Laryngeal Paralysis & Polyneuropathy (JLLP)

A stethoscope sits on top of a medical diagnosis that reads Canine Juvenile Laryngeal Paralysis & Polyneuropathy

Canine Juvenile Laryngeal Paralysis & Polyneuropathy is a hereditary condition that primarily affects certain dog breeds, including Labrador Retrievers, Golden Retrievers, and Bouvier des Flandres. This condition is associated with progressive muscle weakening and paralysis in their larynx, leading to difficulty breathing and voice changes.

The exact cause of JLLP is still unknown, but it’s believed to be inherited as an autosomal recessive trait. This means that both parents of an affected dog must carry the gene mutation for their offspring to develop the condition. Genetic testing can be done to identify carriers of the gene and help breeders make informed decisions to prevent the spread of JLLP.

Symptoms of Canine Juvenile Laryngeal Paralysis & Polyneuropathy usually appear in affected dogs between the ages of 3 months and 1 year. The most common symptom is a change in the dog’s bark, which can become hoarse or weak. Other symptoms include difficulty breathing, especially during exercise or in hot weather, coughing, gagging, regurgitation, and exercise intolerance. As the condition progresses, affected dogs could also have weakness in their hind limbs, leading to difficulty walking or a wobbly gait.

Diagnosing JLLP is typically based on clinical signs and physical examination findings. Additional tests, such as laryngoscopy to visualize the larynx or electromyography to assess muscle function, could be recommended to confirm the diagnosis. Genetic testing can also be used to identify the specific gene mutation associated with JLLP.

Unfortunately, there is no cure for JLLP. Treatment options focus on managing the symptoms and improving the dog’s quality of life.

Symptoms of Canine Juvenile Laryngeal Paralysis & Polyneuropathy

A golden retriever laying on a vet's table.

Symptoms of Canine Juvenile Laryngeal Paralysis & Polyneuropathy typically manifest in affected dogs between the ages of 3 months and 1 year. The most common symptom is a change in the dog’s bark, which usually become hoarse or weak. This change in vocalization is often one of the earliest signs noticed by owners.

Dogs with JLLP can have difficulty breathing, especially during exercise or in hot weather. They can cough, gag, and regurgitate food or water. Exercise intolerance is also commonly seen. The weakened laryngeal muscles make it harder for affected dogs to engage in physical activity.

As the condition progresses, affected dogs can develop weakness in their hind limbs. This can lead to difficulty walking and a noticeable decrease in coordination. In some cases, dogs will even become completely paralyzed in their hind limbs.

Other symptoms that can be present include weight loss or difficulty maintaining a healthy weight, excessive panting, and increased respiratory effort. Dogs with JLLP could also have signs of fatigue and lethargy.

It’s important to note that the severity of symptoms can vary among affected dogs. Some dogs will only have mild symptoms, while others could have more severe symptoms that significantly impact their quality of life. The progression of JLLP can vary, with some dogs having a gradual decline in muscle function over time, while others might deteriorate more rapidly.

Diagnosing Canine Juvenile Laryngeal Paralysis & Polyneuropathy

A person is petting a dog.

Diagnosing Canine Juvenile Laryngeal Paralysis & Polyneuropathy typically involves a combination of clinical examination, medical history evaluation, and diagnostic tests. A thorough assessment by a veterinarian experienced in diagnosing and managing JLLP is essential for an accurate diagnosis.

During the clinical examination, the veterinarian will evaluate the dog’s overall health and perform a physical examination. They will pay special attention to the larynx and assess for any abnormalities or signs of muscle weakness.

A medical history evaluation will also be conducted, which will involve asking the owner about the dog’s breed, age, and any specific symptoms they have noticed. The veterinarian will also ask about the dog’s family history to determine if there is a genetic predisposition to JLLP.

Stages of the Canine Juvenile Laryngeal Paralysis & Polyneuropathy

Canine Juvenile Laryngeal Paralysis & Polyneuropathy can be split into different stages based on the progression of symptoms. It’s important to note that not all dogs with JLLP will progress through all stages, and the rate of progression can vary.

Mild Symptoms Stage 1:

In the early stage of JLLP, dogs will have mild symptoms such as a hoarse or weak bark, occasional difficulty breathing during exercise, and occasional coughing or gagging. These symptoms might not significantly impact the dog’s daily activities.

Moderate Symptoms Stage 2:

In this stage, the symptoms of JLLP become more pronounced. Dogs will have increased difficulty breathing, especially during exercise or in hot weather. They could have frequent episodes of coughing, gagging, and regurgitation. Exercise intolerance and weakness in their hind limbs could also become more apparent. These symptoms start to impact the dog’s daily activities and quality of life.

Severe Symptoms Stage 3:

In the severe stage of JLLP, dogs will have significant difficulty breathing even at rest. They could have frequent episodes of choking or aspiration pneumonia due to the paralysis in their larynx. Dogs could have complete hind limb paralysis and struggle to walk or stand. Weight loss, excessive panting, and increased respiratory effort are common. Fatigue and lethargy could be present as well. These symptoms greatly impact the dog’s quality of life and require immediate medical attention.

Treating Canine Juvenile Laryngeal Paralysis & Polyneuropathy

A female veterinarian is petting a husky dog.

Treating Canine Juvenile Laryngeal Paralysis & Polyneuropathy typically involves a combination of medical management and surgical intervention. The specific treatment plan will depend on the severity of their symptoms and the individual needs of the dog.

Medical Management:

  • Medications: Dogs with JLLP can be prescribed medications to manage their symptoms. These can include anti-inflammatory drugs to reduce inflammation in their larynx, bronchodilators to help with breathing, and cough suppressants to alleviate coughing episodes.
  • Physical therapy: Physical therapy exercises and techniques can be recommended to help improve muscle strength and coordination. This can help them maintain mobility and improve their overall quality of life.

Surgical Intervention:

  • Laryngeal tieback surgery : Laryngeal tieback surgery is a common surgical procedure used to treat dogs with JLLP. This surgery involves permanently opening one or both sides of their larynx to improve airflow and alleviate breathing difficulties. The procedure helps to reduce the risk of choking and aspiration pneumonia.
  • Other surgical interventions: In some cases, additional surgeries could be necessary to address specific complications or symptoms associated with JLLP. For example, if a dog has hind limb paralysis, surgery should be performed to address the underlying polyneuropathy.

The prognosis for dogs with Canine Juvenile Laryngeal Paralysis & Polyneuropathy can vary depending on the severity of their symptoms and their overall health. With appropriate treatment and management, many dogs with JLLP can have improved quality of life and long-term survival.

Preventing Canine Juvenile Laryngeal Paralysis & Polyneuropathy

Preventing Canine Juvenile Laryngeal Paralysis & Polyneuropathy can be challenging because the condition is typically inherited. There are some steps that can be taken to reduce the risk or severity of the disease:

  • Breeding selection: Responsible breeding practices can help reduce the incidence of JLLP. Avoid breeding dogs with a known history of JLLP or dogs that are genetically predisposed to the condition.
  • Genetic testing: Prior to breeding, dogs can be tested for the genetic markers associated with JLLP. This can help identify carriers and prevent them from being bred, reducing the risk of passing on the disease to future generations.
  • Environmental management: Avoiding excessive exercise and exposure to extreme temperatures can help minimize stress on an at risk dog’s larynx and nerves. It’s important to provide a safe and comfortable environment for affected dogs to prevent exacerbation of their symptoms.
  • Early detection and intervention: Regular veterinary check-ups can help detect JLLP early on, allowing for prompt treatment and management. Being proactive in monitoring the health of at-risk breeds can greatly improve the prognosis for affected dogs.